Search results for "Support design"

Chapter 8 Native and Bonded Silicas in Aqueous Sec

1988

Publisher Summary This chapter deals with the properties of packings and columns in correlation to chromatographic separations in size exclusion chromatography (SEC) and provides guidelines for optimum support design. The chapter provides a survey of the current state-of-the-art with respect to the surface modification of silica for SEC packings in aqueous eluents. The properties of commercial packings and columns are listed and compared. An advice is also discussed on the operation and maintenance of columns with a view to achieving high resolution and long life-time. In SEC, solute elution is based on equilibrium, entropy­-controlled size exclusion process. According to their size, the so…